PEMer package contains the computational codes and documentations for the algorithm developed to construct and analyze structural variants (SV) described in .
The package is composed of three modules, PEMer workflow, SV-Simulation and BreakDB. PEMer workflow is a sensitive software for detecting SVs from paired-end sequence reads. SV-Simulation randomly introduces SVs into a given genome and generates simulated paired-end reads from the ‘novel’ genome. Subsequent analysis with PEMer workflow on the simulated reads can facilitate parameterize PEMer workflow. BreakDB is a web accessible database developed to store, annotate and dsplay SV breakpoint events identified by PEMer and from other sources.
PEMer package can be downloaded from here.
 PEMer: a computational framework with simulation-based error models for inferring genomic structural variants from massive paired-end sequencing data, Korbel JO, et al., Genome Biol. 2009 Feb 23;10(2):R23. [PUBMED]
Last updated 05/26/2009 (this site is permanently hosted also at http://sv.gersteinlab.org/pemer)